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Understanding Bodyweight and Glycogen Depletion

If you are dieting or are planning to start a diet, you need to understand the connection between bodyweight and glycogen, that is how carbohydrates get stored in your liver and muscles, so you don’t overestimate your weight loss as you cut carbs—or your weight gain if you add some back. Understand the connection and you’ll have a much better chance of keeping your cool for the long-haul when swings inevitably happen.

So what exactly is going on?

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Seth Roberts and the Shangri-La Diet

I cite Seth Roberts’ blog a great deal over at Linked Down. Seth is a Psychology Professor at Berkeley and an avid self-experimenter. I’ve learned a great deal from subscribing to his blog.

For those who don’t know, Seth Roberts created the Shangri-La Diet, which is a diet centered around reducing the association between flavor and caloric load. I haven’t read the book, so this is an approximation of how it works, but the gist is that the more correlated taste is to caloric load, the greater hunger can be, the harder it will be to cut calories, and the higher your body’s set point for weight will be. “SLD” hacks this relationship via ingesting flavorless calories within certain windows of time. These flavorless calories reduce the brain’s association of high energy density and high flavor. Interestingly enough, the macronutrient source of the calories may be unimportant: you can do SLD with oil, sugar water (so long as it is flavorless), or nose-clipping while eating protein. If you’re skeptical about this diet, I suggest taking a trip over to the SLD Forums and be prepared to see plenty of evidence that SLD works.

Even as I have not tried SLD, it is a fascinating idea and it seems that anyone who is serious about better understanding why we gain weight and what regulates hunger and adiposity must take it seriously enough to figure out how it fits into the big picture of human health. Barring that gargantuan task, it’s at a minimum another way to try and hack weight loss if your current regiment isn’t cutting it for you.

I mention all of this because I stumbled on a 2008 interview between Roberts and Gary Taubes, author of Good Calories, Bad Calories, which I’ve blogged about exhaustively. What a great thing to find that two people I admire had a thoughtful discussion and, even better, said discussion has been made available to me?

Blogging, science and the internet FTW.

Back to trying to understand how SLD fits into the grand scheme of human physiology. An interesting comment was made at the bottom of Part 13 of Roberts’ Interview of Gary Taubes:

I’ve thought a lot about how consuming tasteless food could supress hunger. My favorite theory is that it is similar to what happens when an animal is hibernating. The “magical” appearance of calories fools your body into thinking it is living off its fat and then it actually does so.

This comment reminded me of how the metabolic pathways while fasted are the same as when we consume a diet of only fat and protein. One effect of low-carb diets is appetite suppression. Could the common theme here simply be that both SLD and low-carbohydrate diets and/or fasting act to “trick” our bodies into switching to a non-hungry state?

Obviously that can’t be the entire picture because insulin is the storage hormone that is unleashed by carbohydrate consumption (though less so with fructose).

This issue is worthy of further thought.

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James Hogan’s Four Principles for Effective Dieting

http://jhogan.livejournal.com/73389.html

James Hogan recently posted his “four principles for effective dieting,” which were developed from his personal experience with dieting. It’s a great read on what has worked for James (and as he says, this is a nine-year trend in the making). Comparing notes to my own experiences (Better Health via IF and Low-Carb), I see a lot of overlap. In particular, regular measuring, incremental change, and intermittent fasting (which somewhat translates into Johnson’s Up-Day Down Day) all worked well for me. Of all of those things, I think fasting is the best way to improve your habits because it so starkly breaks rank with existing eating habits.

I also really liked how Hogan articulates targeting the “Healthy Stretch.” I liken this to falling into the dieting “zone.”

Anyway, it’s worth the read in full, so I’m just going to excerpt James’ the four top-level principles:

  • Manage your motivation — “So, the most important thing you can do while losing weight is to successfully manage your motivation.”
  • Use data — “Measuring and using data helps us in two ways. It helps us understand the consequences of our actions more accurately than we’d otherwise be able to. It’s also motivating.”
  • Try different approaches — “Try different approaches. Observe which pieces work (and keep them) and which don’t work (and discard them). Don’t become disheartened if an approach fails …”
  • The alternate-day diet — “The structure of the diet is that you eat a very low number of calories some days (20-50% of the amount required to maintain your weight — your “break even” amount), and a higher number of calories on alternate days. If you’re trying to lose weight, you might target closer to 20% on the “down days,” and if you’re trying to maintain your weight, you might target closer to 50%.”

Finally, I like noting that I know James through Patri through the Seasteading Institute. I suppose I know Patri from having read David Friedman’s blog originally and stumbling into Patri’s works on the old Catallarchy site. What’s fun about these somewhat unpredictable connections is that my old childhood (and adult friend – he was a groomsman of mine) friend Andy happened to be the primary creator/writer for Johnson of the UDDD. The internet: making the world a smaller place a day at a time.

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Five tips to lean out from Brad Pilon

http://bradpilon.com/2009…r-shredded.html

— Below is my comment that I left on Brad’s blog

Brad,

Thanks for the post! Quite a response you’ve garnered, which I can only assume is a testament to the truth your words contain! Your #3 comment reminds me of something you have previously said, which I’ll paraphrase as, “Eat to gain muscle and diet to lose fat.”

One method I use to somewhat reliably keep a pulse on my cutting progress is to take on a regular basis a bare chest, mirror snapshot with my cameraphone. Consistency here is important; I usually take mine after working out and before hitting the shower. Consistent lighting and distance from the mirror are also important, but pretty easy to replicate in your own bathroom. This habit (OCD?) is easy to do and hones a dieter’s ability to see where he’s making progress (or not).

Thanks to Eat Stop Eat / intermittent fasting (and heightened carb-awareness) I’ve managed to hack a lot of body fat off while putting on lean mass via kettlebell training, a three month stint with crossfit, and just general weight-lifting. Today, I am noticeably more lean than I was a year ago when I first experimented with fasting even as I only weigh about five pounds less. My weight went from about 182 to 163 and is now around 175. That’s a leaner 175 than 163!

Even so, and as I had alluded to in a prior comment, I have hit a wall on leaning out. I’ve observed firsthand how exercising more has been sine’ed away via larger meal portions, snacking (even on jerky!), cheating, or whatever. I know that with a little practice I can get everything dialed-in and finally see the coveted six-pack. It just takes a little patience. I remind myself that for most of my life (I’m 28) I’ve been soft around the edges, and it’s reasonable to assume that it may take some time and practice to whittle away the fat that’s been hanging on for the past twenty years.

Thanks again!

— And below are the bullet points on Brad Pilon’s 5 tips to get “super shredded:” you’ll have to go to his site for the details! —

  1. Give yourself permission to get “light”.
  2. Give your diet the opportunity to do the work for you.
  3. Avoid using Cardio to Compensate.
  4. Don’t let the Sine Wave get you.
  5. MEASURE, Measure and measure some more.
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Sugar on the brain

Is sugar another addictive white powder?

A recent study suggests sugar may be addictive. Below are parts of the U.S. News article summarizing the experiment and interpretation of the findings. I suggest reading them all:

“Our evidence from an animal model suggests that bingeing on sugar can act in the brain in ways very similar to drugs of abuse,” [said] lead researcher Bart Hoebel . . .

“Drinking large amounts of sugar water when hungry can cause behavioral changes and even neurochemical changes in the brain which resemble changes that are produced when animals or people take substances of abuse. These animals show signs of withdrawal and even long-lasting effects that might resemble craving,” . . .

A “sugar addiction” may even act as a “gateway” to later abuse of drugs such as alcohol . . .

For the new research, rats were denied food for 12 hours a day, then were given access to food and sugar (25 percent glucose and 10 percent sucrose, similar to a soft drink) for 12 hours a day, for three to four weeks.

The bingeing released a surge of the neurotransmitter dopamine each time in the part of the brain involved in reward, the nucleus accumbens. “It’s been known that drugs of abuse release or increase the levels of dopamine in that part of the brain,” Hoebel said.

But it wasn’t only the sugar that caused this effect, Hoebel explained — it was the sugar combined with the alternating schedule of deprivation and largesse. . . .

But longer periods of abstinence didn’t “cure” the rats. Instead, there were long-lasting effects with the animals: They ingested more sugar than before, as if they were craving the substance and, without sugar, they drank more alcohol.

My anecdotal experience confirms the above findings. For one, the more I have abstained from sugar and refined carbohydrates (the latter of which are one tiny step away from being sugar), the easier it has become to strictly avoid sugar/carbohydrate-dense foods. This suggests to me that the addiction can be controlled by almost completely abstaining from the “drug,” sugar in this case.

Of note, however, is that in those instances when I have fallen off the wagon* and started eating sugar/refined carbs, I tend to overeat/binge. Is this the behavior of an addict? Or is it the psychological response to the forbidden fruit? Or is it a predictable response of treating a diet like a binary system? I.e. going from strict adherence to the diet to “Well I already ate that candy, might as well have some ice cream, too!” Any of these are plausible explanations for my behavior.

The alcohol angle is fascinating: I’ve experienced a clear connection between alcohol and carbohydrate-binge-eating. As before, I am unclear how the alcohol is catalyzing my reaction — is it that alcohol impairs my judgment, handicapping my will power? Or could it be more fundamentally metabolic — the alcohol spurs a chemical reaction resulting in craving sugar/refined carbohydrates? Why do I go from having little-to-no craving for French fries and tator tots to no-holds-barred “pass the ketchup now!” after downing three or four beers.

I have previously blogged on how hard liquor has zero carbohydrates. I’ve since learned that hard liquor (i.e. whiskey) will cause an insulin response even though there are no carbohydrates in the alcohol. Could insulin have something to do with this#?

This study, rather than confirming something I’ve suspected about the addictive nature of sugar, leaves me with more questions than answers. Is modern man doomed to be addicted to sugar? Is sugar addiction similar to alcoholism in that the only successful means to control the addiction is to avoid entirely the addictive substance? Can abstaining from sugar/refined carbohydrates make the addiction worse? Is sugar a poison that should be taken in small doses to control its ill-affects (A particularly strange notion)?

It seems there are more questions than answers. However, I maintain that sugar in any close-to-raw form is unnatural, which means that our evolutionarily designed bodies are inept at handling it. And it seems reasonable to conclude that, even if I tend to overeat refined carbohydrates when I do consume them, over the long-term, I’m still drastically reducing my intake of sugar and refined carbohydrates by maintaining a lifestyle focused on a low-carbohydrate, natural diet mixed with intermittent fasting.

* How often have you heard the phrase “fallen off the wagon” to describe failure at dieting? I hear it all the time (and use it). Probably just a coincidence, this phrase originates in alcoholism. Here we have a study that paints sugar as being similar to alcohol in its addictive characteristics.

# I can’t help but wonder if insulin is the culprit behind addiction to both alcohol and sugar. Has anyone looked into this?

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Back to basics: Fasting and Fasted workouts

Having returned from India and a month-long hiatus from eating healthy and working out, I started brewing on a strategy to “get back at it” and continue working to my ultimate goal, which is achieving never-before-seen (on me) lean-ness and vasculature.

My approach for most of the summer had been working out about five days a week (doing CrossFit) with daily fasting (i.e. 16 hour fasts daily). I tracked a lot of my daily workouts via my workout blog.

Unfortunately, I ran into any number setbacks as I had a couple long periods where I couldn’t manage to eat right or workout (A two week stint out west and a three week stint in India).

That brings me back to today. I’m going “back to basics,” which for me, was eating breakfast/lunch and the fasting until dinner the following day, with a weight-lifting oriented workout an hour or two before breaking my fast. This method worked for me the first time, stripping away a great deal of fat and focusing my diet/weight-training efforts. This time around, the only tweak I’m implementing is that I will do two fasts per week, lifting on days I break the fast, working out on days I eat, and resting on any day I begin a fast. Per usual, my diet will be carb-light, which means no breads, rices, cereals or starchy vegetables while still allowing for most fruits (apples and berries being preferred), some cheats (ice cream), and alcohol.

Goal is to try this for three weeks, track my progress daily and see how I come out on the other end. Stay tuned.

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“Insulin Control” – what it’s all about!

I subscribed to Mike OD’s The IF Life1 awhile back. Mike is a personal trainer with years of experience who is a big advocate of incorporating intermittent fasting into your life. However, his site isn’t merely about IF. From what I can tell, the IF Life aims to be a holistic resource on living a healthy and happy life. Mike’s site is a great resource — check it out.

In two recent posts on The IF Life, Mike used the phrase “insulin control” to sum up one of the key tenets of effective diets (See here and here).

In the first post, Mike alludes to the fact that insulin control is the chief goal of all effective diets, whether the diets know it or not (I.e. diets that advocate six meals a day are aiming to control insulin spikes, even if they don’t say so explicitly).

In the second linked post, titled Diet Book Insanity. When did Eating become this Complicated?, Mike states:

Now I know what many may say, but diets can work right? Sure … at the heart of all diets you see 2 main things that will get people results: Insulin control (see the carbs are not the enemy post and insulin and sugar post) and Calorie Deficit Intake (so the body burns from internal fuel sources, which is what you need if you want to burn that stubborn body fat).

Mike smartly tacks on caloric restriction to insulin control as the two overarching diet-advice mantras that tend to get results (Almost certainly so when used together). And though this wasn’t really the point of his diet insanity post (and I know I didn’t coin the phrase), I’m still going to take some credit for distilling the diet madness down to two simple words:

They’re all about insulin control!

Update 09/10/08: Robb Wolf, another blogger I’m subscribing to these days, happened to use the phrase “insulin control” back in October of 2007:

Super simple: Our nutritional recommendations are focused at insulin control. You could also say that our nutritional recommendations are what we are designed to eat and thrive on …

The post is about CrossFit, overexercising, and dialing in nutrition in order to see body composition changes. In my (limited) experience, his post rings absolutely true for me: exercise did little in the way to improve my body composition until I reigned in insulin.

1 “IF” stands for “Intermittent Fasting”, of course, and you gotta love the play on words the acronym creates!

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Being healthy on the road

Traveling has an uncanny tendency to thwart healthy routines. It is difficult both to make time for exercise and to eat healthy amidst the bevy of fast food restaurants, hotels, free food, abundant spirits and people who eat differently than me. How do you navigate these health obstructions while on the road?

I’m hardly an expert, but here is how I’m managing to maintain a low-carb diet replete with activity while being away from home:

  • Be active. Some Hollywood star has the following motto: “I try to break a sweat everyday.” (H/T IF Life) This just seems like a robust life-motto that reverberates in my head — a life where you exert enough effort to break a sweat every day just seems right to me.

    On the road, it can be difficult to do this with limited equipment. I like having a kettlebell around, but if you’re flying, you can forget about taking a 35 lb. or 53 lb. kettlebell along for the ride.

    This means you have to improvise. Good ways I’ve found to improvise include running sprints, doing push-ups, and air squats. I’m still trying to find a good pull-up substitute that can be performed with everyday furniture (Any ideas?).

  • Skip a meal or two. Fasting is such a powerful tool to recenter/refocus after finding yourself lost in the bad habits that result from traveling. I’ve found the easiest way to fast is to skip breakfast. Depending on how you’re feeling around lunchtime, feel free to skip lunch, too. I did this yesterday, not eating anything until dinner and I felt great all day and even managed a nice workout compliments of a treadmill and one of those all-in-one weightlifting machines (Improvise!).
  • Go for level-two fast food. I just made up that Level II distinction. What I mean by it is that you should take the extra ten minutes to seek out local restaurants that can serve up some healthier takeout dishes. For me, I’ve eaten a few greek salads with gyro meat or chicken. It’s not ideal but its better than getting a number five combo from McDonald’s.
  • Don’t strive for perfection. When you inevitably cave to cravings and eat that fresh-baked cinnamon bun that was calling your name at the hotel breakfast bar, let it go. Striving to acheive a perfect maintenance of your healthy habits while on the road is a recipe for failure. It’s okay to deviate — just take steps to get back on track (i.e. trying a mini-fast or having an intense workout in the hotel gym).

So that is what I’ve come up with so far. I’m interested to hear any ideas from any readers regarding other ways to be healthy “on the road”. Please comment if you think of something you’d like to share!

Finally, one of the hardest parts about breaking routines is getting back on track after the traveling is over. That topic remains a discussion for another day: though I will say that I’ve found fasting to be an excellent way to “re-rail” post-vacation.

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Insulin Control: The Common Denominator of the Low-Carb / Fasting / Caloric Restriction Diets.

Over the past four months, I’ve turned into a staunch advocate of Paleo / low-carb / intermittent fasting (See IF/low-carb, caloric restriction, ketosis, hormesis). I proselytize because this diet lifestyle has had a significant impact on my physical health and my understanding of nutrition. Unfortunately, it wasn’t long before my advocacy spurred the comment that there is “No zealot like the converted.” Oof!

The retort stuck with me. I am a passionate about spreading good ideas. And this idea concerning the health of my friends and family was not only a good idea in theory, but also one in practice. The last thing I wanted was for my zeal to turn individuals away. I needed a better in than “low-carb” or “fasting”.

Unfortunately, there are a lot of pre-conceived notions and pent-up negative biases towards “low-carb” in specific and diets in general. Most people have experienced nothing but disappointment from dieting and/or strict exercise regiments. When the low-carb meme went mainstream a few years ago, non-believers and skeptics rightfully vocalized their doubt. My own curiosity brought me to read a good portion of Atkins New Diet Revolution; however, I was unconvinced. Atkins’ rhetoric was all pathos and little ethos: I needed the science. Not surprisingly, I never even tried the diet, more or less writing it off as just another fad.

Fast-forward to today. There is an ever-growing number of branded low-carbohydrate diets, and additionally, there are a growing number of diets that incorporate caloric restriction or fasting (Popular examples of low-carb and/or fasting include Paleo / DeVany, Protein Power, Atkins, South Beach, Warrior Diet, The Zone, Eat Stop Eat, Fast-5, UpDayDownDay, Bantingism, etc.). Such a plethora of similar yet nuanced regiments is confusing. Who wants to wade through them all to explain their own method? Who wants to lay caveat upon caveat on a diet to tailor fit it to your own experience just to explain it to an inquisitor? My eyes glaze over just thinking about it!

There is a better way. All of these diets have a clear, underlying purpose: to control insulin. Why not just call it Insulin control?

By starting with this core tenet, I can transcend the diet denominational mess.

Insulin control gets to the heart of the matter, which is that excess or chronic insulin in the blood leads to fat storage, loss of insulin sensitivity / increased insulin resistance, downregulation of fat mobilizing hormones (adrenaline, noradrenaline, glucagon and human growth hormone), and can ultimately lead to symptoms of metabolic syndrome, including hypertension, obesity, cardiovascular disease, diabetes and cancer. How do you control insulin? Insulin control can be accomplished via reduction in carbohydrate intake or via controlling feeding times (via fasting) so that insulin levels sufficiently drop, which allows fat mobilization to resume.

Calling what we do “insulin control” focuses on the problem and implies the solution. It also grounds the diet/lifestyle to its fundamental science while avoiding the pitfalls of bias-loaded words. Starting an argument from “insulin control” gets me to low-carb, to fasting, to evolution, to metabolic syndrome, to higher-fat consumption, to more natural/less process foods. Why bother with the varying brands when it’s all about insulin control!

Further reading:

  • Go here to get started on some fantastic quotes on insulin, sugar, glucose, etc. If you’re not already practicing a low-carbohydrate lifestyle, read up.
  • Art De Vany wrote a reasoned response to the contention that the Paleo / “EF Way of eating” (See how muddled that is!?) was a fad diet. His most excellent point was that the current American diet is much more a fad having been around for merely decades relative to the stacked millennia of two million years (Tyranny of Present fallacy).
  • In mentioning Johnson’s UpDayDownDay diet, Patri Friedman notes how excellent it is that such a variation of research is occurring surrounding caloric restriction. What I wonder: is caloric restriction / fasting an emerging diet trend? I plan on doing a tiny blog on this later. Stay tuned.
  • While I was writing this entry, the IF life published a diagram that lays out how to stay on track for weight loss. It’s a useful, informative and simple diagram. And what will you note in the middlemost bubble? Control insulin!
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Improve your Health via Hormesis – Stress Out.

As alluded to previously, injecting small doses of stress into an otherwise harmonious existence can improve your health. This phenomenon is called hormesis. Here’s a googled definition of hormesis:

A dose response phenomenon whereby a substance that in a high dose inhibits (or is toxic to) a biological process, in a much smaller dose will stimulate (or protect) that same process.

Toxic substances stress us. Stephan explained it nicely over at Whole Health Source:

Hormesis … increases resistance to other, more intense or chronic stressors. It can increase resistance to a variety of stresses, not only the one to which you are exposed.

Hormesis is a powerful, non-obvious-yet-evolutionarily-intuitive idea — I can improve my health by intentionally introducing some stress into my otherwise pampered, stress-free life. And here are a few applications:

  • High-intensity exercise. I lump in here anything that briefly elevates my heart-rate and requires my body to do a significant amount of work. Weight-lifting, sprinting and kettlebell drills readily come to mind.
  • Fasting / Intermittent Fasting. Going without food is quite possibly the easiest path to the benefits of hormesis. Shameless self-promotion: on fasting (application and benefits) and more recently on caloric restriction / resveratrol and the potential for slowing aging.
  • Drinking alcohol. We’ve heard this before — drinking one to two alcoholic beverages a day may benefit cardiovascular health. It seems that the benefit of drinking alcohol is from its hormetic effect.
  • Smoking tobacco. First, I gleaned this application from Arthur De Vany. Dr. DeVany applies it via cigars. I see no reason it could not also be applied via a pipe or some type of snuff or chew. I personally enjoy the occassional cigar or alternatively, will smoke a pipe. One thing to note: inhaling might eliminate the hormetic benefit of tobacco use by taking it from a mild dose to a heavy dose. I simply don’t know.
  • Cold showers. I snagged this one from Richard Nikoley. I then reread the idea from Art and then Stephan, who says it helps fire up “non-shivering thermogenesis”. If you want to read more about activating cold via hormesis, check out what a DeVany reader sent in on the subject of brief exposure to cold.
  • Radiation. I mention this only for completeness, but small exposure to radiation is a tactic to increase resistance to larger doses of radiation later (Surprise, its controversial). I don’t know of any way for normal folks to apply radiation hormesis.

The above are fairly non-controversial ways to practice “stressing out”, and thereby benefit from hormesis (Excepting radiation hormesis). However, I wonder if there are other things one could do. Here are some alternative hormetic possibilities:

  • Get less sleep. Maybe periodically cut back on your sleep by 30%. I’ve occasionally experienced increased alertness on less sleep. However, the positive effect wears off in time. Prolonged lack of sleep also weakens your immune system, which doesn’t sound too beneficial.
  • Binge on fruit. Assuming you are a low-carber, eating a lot of fruit at one time should result in a sizeable insulin response. If you aren’t on a low-carbohydrate diet, binging on fruit won’t do much to acutely stress your body.
  • Get some sun. Beneficial for Vitamin D purposes, seems like this would also make sense for potential hormetic effects.
  • Expose your kids to allergens. Didn’t know for sure where to put this one and I don’t have kids. However, I’ve read that exposing your kids to cats may reduce the risk of allergies and asthma. Is the benefit here hormesis? Also, is there a risk in overprotecting your kids from germs?

If you have any other ideas for unconventional applications of hormesis, I would love to hear them.

Finally, let’s remember that high doses of toxic substances can impair your health or even kill you. High doses of stress are likewise unhealthy. Therefore, may I present one last list of bad ways to stress out:

  • Over-training (And also, potentially, endurance exercise). Not allowing your body to recover from exercise is a recipe for disaster. Endurance activities like running marathons (or jogging long-distances) might also be harmful (Art De Vany thinks so). I speculate that endurance activities may be safe so long as they are using fat oxidation for energy (See endurance athlete Mark Twight’s write-up on fat). This would necessarily require a lower intensity for most all of us who don’t train to exercise for hours on end — an effort probably no more intense than walking or leisurely riding a bike.
  • Stressing about work, money, family, relationships, career, or the meaning of life. We’ve all done this. However, can you imagine our evolutionary ancestors experiencing existential angst? I can’t. Food availability, yes. Finding shelter, sure. Avoiding predators, certainly. I’m no expert on meditation or any other specific methods for stress reduction. When I get stressed out about life for too long, I just try and step back and see the big picture and/or let go. It helps.
  • Cut back on the caffeine. This is a tough one for me. I drink a good bit of coffee on a daily basis. Caffeine might have hormetic benefits — but I doubt they occur if you’re a chronic user like me.

Anything I missed? If so, please let me know.

Parting thoughts: introduce some “stress” to your life and improve your health. A cold shower followed-up by a 24-hour fast is an easy way to get started. Finish off the fast with some hill sprints. Practice hormesis. If you can consciously control the stressors in your life, you just might live longer.