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Understanding Bodyweight and Glycogen Depletion

If you are dieting or are planning to start a diet, you need to understand the connection between bodyweight and glycogen, that is how carbohydrates get stored in your liver and muscles, so you don’t overestimate your weight loss as you cut carbs—or your weight gain if you add some back. Understand the connection and you’ll have a much better chance of keeping your cool for the long-haul when swings inevitably happen.

So what exactly is going on?

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“Their minds close and they turn around and go back to their lives.”

http://www.blog.sethrober…art-14-the-end/

I did a site search on Seth’s blog for “fructose” (On how to do these and improve your use of Google Search) as I was curious if Roberts had seen any negative impact to using fructose in his Shangri-La Diet. I wondered this because fructose is apparently sweeter than glucose, which per the SLD theory that flavor/calorie associations spur weight gain, might imply that ingesting fructose would actually cause weight gain (I was trying to tie this all together into Stephen at WHS’s recent post about sugar). Alas, apparently sugar-water using nothing but fructose works fine on SLD. I forgot that plain sugar water is tasteless regardless of the sugar used (I don’t understand how sugar is sweet, but sugar water is not, but it’s true)

Anyway, in a roundabout way I got to reading Roberts’ interview with Taubes (Only read the last two parts out of fourteen: need to find the time to read the rest!). It was at the end of this interview that Taubes made a fascinating comment about how people in the scientific community react to his research on insulin and carbohydrates. Specifically, these otherwise intelligent and reasoning folk tend to close their minds as soon as Taubes drops the “C word:” carbohydrates. One word shuts them down as they write off Taubes’ immense research by way of invoking the “Atkins diet” or any number of other “low-carb diets” that were all the rage a few years ago.

And I couldn’t help but think how this mental shutdown is what I’ve seen countless times with any person of religion — people who otherwise may agree with any number of points you make will completely shutdown on the invocation of certain words.

This is a fantastic example of rational people utterly failing to apply reason, and it is exemplified by scientists and people of faith, alike. Indeed, the common thread here is simply dogma. Interesting.

TAUBES I think that’s true, but there’s this contrary effect that happens. I said this in my lecture. The science I’m trying to get across can be accepted up until the point at which I say the the word carbohydrate, and then people shut down, and they think “Oh, it’s that Atkins stuff again.” Their minds close and they turn around and go back to their lives. Anyway, I look forward to seeing the interview and getting your book and reading it. I enjoyed this. Again, I like nothing better than talking about this stuff.

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Superfluous Fluids: Don’t Drink Calories (But milk may be ok)

http://www.bodyrecomposit…rch-review.html

Lyle McDonald of bodyrecomposition.com consistently puts out in-depth, even-keeled analysis on exercise and nutrition. I don’t always buy his conclusions, but he clearly knows his stuff and shares a great deal of knowledge freely on his site. His frank take can be funny, too.

Lyle has previously gone into great detail on milk as a sports drink. Milk has protein, fat and carbohydrates, which makes it more of a liquid food than a drink. Mother nature concocted the mix, so it has that going for it as far as the biological “benefit of the doubt.” Whether humans are evolutionarily designed to drink cow milk is another question. Suffice to say that it’s a hotly debated topic amongst the Paleo crowd.

I still enjoy cheese and (occasionally) ice cream.

In this particular article, Lyle discusses a paper that examined the impact on the human body of consuming “milk, beer, wine, tea, coffee, distilled alcoholic beverages, juice and soft drinks.” The big takeaway is simple: Don’t drink your calories except maybe milk.

Why? Apparently our bodies aren’t good at accounting/adjusting for the energy. This failure causes two problems: not only do our bodies fail to adjust overall caloric intake to account for the consumption of a Coke or Snapple, drinking these “empty calories” may result in overconsuming other foods! Talk about a double-whammy to your waistline!

Even though Lyle often goes middle-of-the-road where others end up more extreme (I.e. low-fat, or low-carb diets), this is one of the few times where he actually more or less makes an outright nutrition rule, which is that sugary drinks have no place in the human diet. He couples this thought with the tangential point that the demonization of HFCS is a distraction: raw sugar (i.e. diluted in water), no matter the form (glucose, sucrose, whatever), is the problem.

And honestly, how is this conclusion not obvious? Don’t drink sugar!

Other thoughts outside of Lyle’s take: I’m reminded of Seth Roberts of Shangri-La diet fame. Shangri-La asserts that the stronger the flavor/calorie association by our bodies, the more weight we will put on. I wonder if this is coming into play here in that sugary beverages typically are drank in concert with a meal. This results in more flavor and more energy density, heightening the Pavlovian association and raising “set point” (this is all based on my rudimentary understanding of Shangri-La). On the other hand, it makes it harder to explain how flavorless sugar water can cause appetite suppression if our bodies generally fail to register the calories. My hunch is that there is a more complex relationship here.

And one other thought: Lyle notes that for most of human existence the only liquids known to man were breast milk and water. Makes sense. Only one problem: human beings drank what, for lack of a better term, I’m going to call “wild water.” I have no idea what wild water was composed of as far as bacteria, nutrients, and minerals. However, I’m confident that it was not like the water we get from the tap or the filtered Brita stuff.

So maybe Coca-Cola should look into a new bottled water market — and yes, if they call it “wild water” I will seek royalties!

Looking globally, drink patterns have shown massive growth with soda products being consumed at a rate in excess of one billion drinks per day (makes you wish you’d bought stock, huh?). Beer consumption has shown the greatest increase with tea showing a slight increase. Wine and milk consumption have fallen globally, presumably due to the introduction of all the drinks that have made America rich, proud and very fat (my comment, not theirs).

The next section of the paper got into what is arguably the most important issue of the paper: the simple fact that for all but the last 11,000 years, the predominant fluids consumed by humans were water and breast milk and nothing else. Now, they go out of their way to point out that milk is a complete beverage containing protein, carbohydrate, fat and water. Water is, of course water which provides no calories. This is important because numerous studies have shown that humans show poor compensation for fluid calories.

Let me explain that a bit. Compensation means that the body will adjust caloric intake at other times of the day (or days later) for a given caloric load. So say you eat a bunch of candy earlier in the day and it provides 450 calories. What you might see is that, later in the day, folks eat a few hundred calories less than they’d normally eat. The body ‘compensates’ for the food you ate earlier. The problem is that most liquid calories aren’t compensated for well and figuring out why is of some interest to researchers.

This is also a big part of why all of the furor over HFCS is mis-placed in my opinion: the problem isn’t with the HFCS per se, it’s the form that people are getting it which is liquid calories. Which the body doesn’t compensate for well. But the body wouldn’t compensate any better for a sucrose containing drink, a glucose containing drink or any other caloric drink. Get it?

It’s got nothing to do with the HFCS content, it’s got to do with how the human bodyhandles non-milk caloric fluids. . . .

Of some interest (especially to me since I like jelly beans) one study compared the intake of 450 kcal or jelly beans to 450 kcal of a soft drink. the jelly bean consumers actually reduced their food intake by slightly more than the 450 calories in the jelly beans (Coming soon: the Jelly Bean Diet) later in the day.

The carb containing soft drink group not only failed to compensate for the drink but also increased their intake of other foods slightly. That is, not only did they get the added calories from the soft-drink, they ate more food as well; a double whammy in terms of weight gain. . . .

The sight and smell of foods also affects hormonal response, there is something called the cephalic insulin response for example, insulin can go up when people smell or taste sweet foods, long before it hits the bloodstream. Someone in the comments of one of my articles asked about sugar free drinks and it’s relevant here as they can stimulate insulin response in some folks; I’ll have to do a full feature on this at a later date [JNO: See Artificial Sweeteners and Energy Disregulation for a little more]. . . .

Carbohydrates alone stimulate the least number of appetite blunting factors, protein and fat stimulate the release of more. So you’d expect much less of a compensatory response to a drink containing protein and fat (think lowfat milk) as compared to one containing only carbohydrate (think fruit juice or a high sugar soda). Which is exactly what the studies have shown. Milk shows a nice normal compensation to intake; it’s effectively a liquid ‘food’. Sugar sweetened soft drinks show no compensation.

So folks living on sugary drinks are causing themselves major problems. Not only do the drinks themselves have scads of calories, the body doesn’t compensate for their intake. So all of those calories essentially end up being ‘added’ to the normal food intake (which is just as often awful in folks who drink lots of soda). In some people, the sweet taste seems to drive intake of other sugary foods so it’s a double whammy.

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Why You Got Fat (Fat Head Review)

http://www.freetheanimal….ou-got-fat.html

Richard Nikoley recently received, watched and reviewed Tom Naughton’s documentary (mockumentary?) Fat Head. I had a very similar general take on the movie to Richard’s, so I’m going to echo his comments by way of blockquote:

It’s really two movies in one. In the first part, he thoroughly discredits that lying, opportunist bastard, Morgan Spurlock. Tom Naughton also goes on a fast food diet for a month, but a sensible one, keeping total calories to about 2,000, and total carbs to 100 grams (400 calories, so 20% of total kcals). He loses about 8-10 pounds, as I recall, and most of his blood work is improved.

The second half (the best) is about the awful state of nutrition science and dietary advice in America. Naughton even employs an evolutionary basis, as seen here.

Just to expound on this review, I found the second half of Fat Head to be much more interesting and compelling than the first half (even though Naughton does a plenty thorough job debunking Spurlock, I just didn’t really care — I never saw Super Size Me!).

The particular clip from Fat Head Richard posted in his review was one of the best parts of the movie as it humorously explains the relationship between blood sugar, fat cells and insulin. Check it out:
[video:youtube:mNYlIcXynwE]

One other clip from the movie that isn’t available for preview online talked about the glycemic index and visually displayed how certain foods digest into whatever equivalent amount of sugar.

Richard gives an example of this conversion with regard to a soda:

Consider this: for the average person with normal blood glucose levels, you have about the equivalent of one single teaspoon of sugar circulating in your entire body. One. Single. Teaspoon. So, what that means is that when you drink a regular Coca Cola at 27 grams of carbohydrate . . . you are ingesting . . . over 5 times the amount of sugar as is contained in your entire body. How about an 8 oz. glass or orange juice? Same thing (26 grams). Now, consider that as you go throughout your day. Look at food labels, and divide the amount of carbohydrate by 5 to see how many times your total blood sugar you’re ingesting all at once.

Richard’s rule of thumb for conversion is great because I can visualize a teaspoonful of sugar. Take a bowl of Raisin Bran. A serving has 45 grams of carbohydrates, 7 of which are fiber, so net 38 grams plus the 12 grams from a cup of milk. 50 grams of carbohydrates converts to 10 teaspoons of sugar in your bloodstream. That’d be a nice pile of sugar.

This mental picture conversion of carb-heavy foods to teaspoons of sugar is a powerful way to help people connect the dots between “ingesting lots of sugar is bad for you” to “ingesting lots of carbohydrates is bad for you.” Even as this is an oversimplification of a more complex macro-nutrient problem, it’s still a better way to guide your eating behavior as compared with our current, asinine low-fat-equals-health insanity.

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How to Eat Grains

http://wholehealthsource….eat-grains.html

Continuing the recent interest in fermentation (See discussion of Seth Roberts’ posts on Probiotics and Your Immune System and The Staggering Greatness of Homemade Yogurt) comes this post from Stephan at Whole Health Source discussing how to eat grains.

There are two ideas that seem to be repeatedly coming to the surface here:

  • Carbohydrates seem to be better for human consumption when fermented as fermentation reduces anti-nutrients and even introduces some new nutrition in the process.
  • Foods that don’t seem “paleo” at first blush maybe just need some fermentation, which is really just another way of saying they need to be pre-digested prior to eating.

Regarding that second point, our hunter/gatherer ancestors had little food storage tech. This has two implications in my mind:

  • Food is consumed fresh if at all possible, to the point of gorging. Our bodies have an amazing ability to store excess carbohydrate consumption efficiently as fat.
  • Food found but not readily consumed rots or ferments. Our bodies do well with this (Evolutionary luck or design?) by receiving immune system boosts from the introduction of bacteria, reducing toxins via fermentation and maximizing nutrient absorption.

Anyway, here is Stephan:

The second factor that’s often overlooked is food preparation techniques. These tribes did not eat their grains and legumes haphazardly! This is a factor that was overlooked by Dr. Price himself, but has been emphasized by Sally Fallon. Healthy grain-based African cultures typically soaked, ground and fermented their grains before cooking, creating a sour porridge that’s nutritionally superior to unfermented grains. The bran was removed from corn and millet during processing, if possible. Legumes were always soaked prior to cooking.

These traditional food processing techniques have a very important effect on grains and legumes that brings them closer in line with the “paleolithic” foods our bodies are designed to digest. They reduce or eliminate toxins such as lectins and tannins, greatly reduce anti-nutrients such as phytic acid and protease inhibitors, and improve vitamin content and amino acid profile. Fermentation is particularly effective in this regard. One has to wonder how long it took the first agriculturalists to discover fermentation, and whether poor food preparation techniques or the exclusion of animal foods could account for their poor health.

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Sugar on the brain

Is sugar another addictive white powder?

A recent study suggests sugar may be addictive. Below are parts of the U.S. News article summarizing the experiment and interpretation of the findings. I suggest reading them all:

“Our evidence from an animal model suggests that bingeing on sugar can act in the brain in ways very similar to drugs of abuse,” [said] lead researcher Bart Hoebel . . .

“Drinking large amounts of sugar water when hungry can cause behavioral changes and even neurochemical changes in the brain which resemble changes that are produced when animals or people take substances of abuse. These animals show signs of withdrawal and even long-lasting effects that might resemble craving,” . . .

A “sugar addiction” may even act as a “gateway” to later abuse of drugs such as alcohol . . .

For the new research, rats were denied food for 12 hours a day, then were given access to food and sugar (25 percent glucose and 10 percent sucrose, similar to a soft drink) for 12 hours a day, for three to four weeks.

The bingeing released a surge of the neurotransmitter dopamine each time in the part of the brain involved in reward, the nucleus accumbens. “It’s been known that drugs of abuse release or increase the levels of dopamine in that part of the brain,” Hoebel said.

But it wasn’t only the sugar that caused this effect, Hoebel explained — it was the sugar combined with the alternating schedule of deprivation and largesse. . . .

But longer periods of abstinence didn’t “cure” the rats. Instead, there were long-lasting effects with the animals: They ingested more sugar than before, as if they were craving the substance and, without sugar, they drank more alcohol.

My anecdotal experience confirms the above findings. For one, the more I have abstained from sugar and refined carbohydrates (the latter of which are one tiny step away from being sugar), the easier it has become to strictly avoid sugar/carbohydrate-dense foods. This suggests to me that the addiction can be controlled by almost completely abstaining from the “drug,” sugar in this case.

Of note, however, is that in those instances when I have fallen off the wagon* and started eating sugar/refined carbs, I tend to overeat/binge. Is this the behavior of an addict? Or is it the psychological response to the forbidden fruit? Or is it a predictable response of treating a diet like a binary system? I.e. going from strict adherence to the diet to “Well I already ate that candy, might as well have some ice cream, too!” Any of these are plausible explanations for my behavior.

The alcohol angle is fascinating: I’ve experienced a clear connection between alcohol and carbohydrate-binge-eating. As before, I am unclear how the alcohol is catalyzing my reaction — is it that alcohol impairs my judgment, handicapping my will power? Or could it be more fundamentally metabolic — the alcohol spurs a chemical reaction resulting in craving sugar/refined carbohydrates? Why do I go from having little-to-no craving for French fries and tator tots to no-holds-barred “pass the ketchup now!” after downing three or four beers.

I have previously blogged on how hard liquor has zero carbohydrates. I’ve since learned that hard liquor (i.e. whiskey) will cause an insulin response even though there are no carbohydrates in the alcohol. Could insulin have something to do with this#?

This study, rather than confirming something I’ve suspected about the addictive nature of sugar, leaves me with more questions than answers. Is modern man doomed to be addicted to sugar? Is sugar addiction similar to alcoholism in that the only successful means to control the addiction is to avoid entirely the addictive substance? Can abstaining from sugar/refined carbohydrates make the addiction worse? Is sugar a poison that should be taken in small doses to control its ill-affects (A particularly strange notion)?

It seems there are more questions than answers. However, I maintain that sugar in any close-to-raw form is unnatural, which means that our evolutionarily designed bodies are inept at handling it. And it seems reasonable to conclude that, even if I tend to overeat refined carbohydrates when I do consume them, over the long-term, I’m still drastically reducing my intake of sugar and refined carbohydrates by maintaining a lifestyle focused on a low-carbohydrate, natural diet mixed with intermittent fasting.

* How often have you heard the phrase “fallen off the wagon” to describe failure at dieting? I hear it all the time (and use it). Probably just a coincidence, this phrase originates in alcoholism. Here we have a study that paints sugar as being similar to alcohol in its addictive characteristics.

# I can’t help but wonder if insulin is the culprit behind addiction to both alcohol and sugar. Has anyone looked into this?

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Gauging Insulin Sensitivity

I originally read Lyle McDonald’s article on Insulin Sensitivity and Fat Loss a number of weeks ago, but I just stumbled upon it again and wanted to jot down, for my own record, his comments on gauging your own insulin sensitivity:

However, in practice, there are signs as to whether you have good insulin sensitivity or not and possibly whether you oversecrete insulin. Here?s two very simple questions to ask yourself regarding your response to diet.

  1. On high-carbohydrate intakes, do you find yourself getting pumped and full or sloppy and bloated? If the former, you have good insulin sensitivity; if the latter, you don?t.
  2. When you eat a large carbohydrate meal, do you find that you have steady and stable energy levels or do you get an energy crash/sleep and get hungry about an hour later? If the former, you probably have normal/low levels of insulin secretion; if the latter, you probably tend to oversecrete insulin which is causing blood glucose to crash which is making you sleepy and hungry.

I’m not sure where I fall on his second test (other than saying that I don’t get sleepy though I do get hungry), but I know where I fall on the latter, which is that I feel bloated. I didn’t realize this until I quit most heavy carbs. Now, when I backslide and load up on carbs, I actually feel my belly distend! Not fun.

This all reminds me of how I’ve thought about where to put my carbohydrates in my meal. For awhile, I thought I should stick them at the end of the meal. I was reasoning that, at the end, they’d take longer to digest, which would further slow the glycemic load.

I don’t think it works that way, however. I recall reading somewhere (I think on Eades’ proteinpower.com) that there could is a significant delay between when you eat carbohydrates and when your brain gets the fullness signal, which is why you can pound a dessert even after you couldn’t eat another bite of steak. Thus, if you put your carbohydrates at the end of your meal, you may feel hungry even after eating a full meal. As a result, I’ve started putting my carbohydrates at the beginning of the meal — and for the record, by “my carbohydrates”, I mainly just mean any fruits or vegetables I am going to eat.

It’s an experiment, so your mileage may vary.

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Quotes on Sugar, Insulin, Glucose, Aging

Via the IF Life comes a smattering of quotes from Dr. Ron Rosedale on sugar, insulin, glucose, carbohydrates, aging, disease, etc. In short, they are all about the importance of insulin control for your health! Here’s one particularly insightful quote:

We only have one hormone that lowers sugar, and that?s insulin. Its primary use was never to lower sugar. We?ve got a bunch of hormones that raise sugar, cortisone being one and growth hormone another, and epinephrine, and glucagon.

Our primary evolutionary problem was to raise blood sugar to give your brain enough and your nerves enough and primarily red blood cells, which require glucose. So from an evolutionary sense if something is important we have redundant mechanisms. The fact that we only have one hormone that lowers sugar tells us that it was never something important in the past.

Okay, one more:

What they are finding on these major centenarian studies is that there is hardly anything in common among them. They have high cholesterol and low cholesterol, some exercise and some don?t, some smoke, some don?t. Some are nasty as can be and some nice and calm and nice. Some are ornery, but they all [have] low sugar, relatively for their age. They all have low triglycerides for their age.

And they all have relatively low insulin. Insulin is the common denominator in everything I?ve just talked about. They way to treat cardiovascular disease and the way I treated my stepfather, the way I treated the high risk cancer patient, and osteoporosis, high blood pressure, the way to treat virtually all the so-called chronic diseases of aging is to treat insulin itself.

For the full Rosedale lecture, go here.

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Mark Sisson: a Contrarian View on Water

A contrarian by nature (Perhaps to a fault), I found Mark Sisson’s recent counter-conventional post on water well worth the read. Bucking the mainstream view that we should drink at least eight glasses (64 oz. total) of water per day, Mark exhaustively details the counterpoint, advocating what seems downright obvious: obey your thirst!

Some takeaways from Mark’s post:

  • We get a lot of water from our food. Mark argues that paleolithic man likely recieved most of his water from food sources. Example: eating fruit will help satisfy your body’s water requirements.
  • Diuretics like coffee, tea and alcohol necessarily contain water, and the diuretic effect only occurs at high, unhealthy doses.
  • Drinking a lot of water before or during a meal can thwart digestion by raising pH levels in your stomach. Raised pH levels can result in indigestion or worse: lowered acidity could reduce the stomach’s ability to destroy susceptible pathogens and other creepy crawlers!
  • The commonly-held mantra that thirst lags dehydration (i.e. “if you’re thirsty, you’re already dehydrated”) is erroneous. Therefore, as one sugary drink prescribes, “Obey your thirst!” with H2O.

Mark packs a lot more into his post, so be sure to read it.

On a related, technical note, in Good Calories, Bad Calories Gary Taubes explains how carbohydrates induce water retention (Fats do not). Assuming I recall correctly, a fat gram has two times the amount of energy as a carbohydrate gram (9 kcal compared to 4). Furthermore, storing a carb gram requires two grams of water. Therefore, energy equivalence between fat and carbohydrates from a volume standpoint is reached at 1:6 fat to carb/water ratio as follows:

1 gm fat = 9 kcal @ 1 gram volume
2 gm carbohydrate + 4 gm water = 8kcal @ 6 grams volume

Thus we see the efficiency of fat as an energy storage vehicle — a whopping 6x as much energy can be stored in the body as fat relative to the volume it would take to store the same amount of energy with carbohydrates!

Between Mark’s comments and Taubes fat-storage efficiency explanation (Would love an online reference here if anyone can find one), I have to wonder: does a low-carb diet go hand-in-hand with lowered water requirements? At first blush, it seems like the answer would be a resounding yes, but I don’t know. Readers?